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What is CHONDROPLUS ?

CHONDROPLUS is a synthetic collagen peptide and hyaluronic acid (HA)- based, viscoelastic gel for the intra-articular treatment of moderate to severe osteoarthritis of the knee.

What should I know about CHONDROPLUS ?

CHONDROPLUS uses synthetic collagen technology which gives it a unique lubricating gel particle structure. The Ctp used in Chondroplus was a highly purified synthetic tripeptide fraction containing Gly-Xaa-Yaa sequences. 

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About CHONDROPLUS

CHONDROPLUS is a single injection to relieve the pain of knee osteoarthritis.

CHONDROPLUS is a synthetic collagen peptide and hyaluronic acid (HA)- based, viscoelastic gel for the intra-articular treatment it is based upon a safe and proven technology. Hyaluronic acid (HA) is a naturally occurring molecule that provides the lubrication and cushioning in a normal joint.

 
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Collagen Tripeptide act of mechanism

  • Unlike "hydrodynamic lubrication" (where a film of liquid keeps surfaces apart), CTP excels at boundary lubrication. This occurs when the joint is under high pressure and moving at low speeds (like standing up from a chair).

  • Surface Coating: Lubricin molecules anchor themselves to the topmost layer of the cartilage (the superficial zone).

  • Steric Repulsion: Because the central domains of the CTP molecules are negatively charged and highly hydrated, they repel each other when two cartilage surfaces come close. This "cushion of repulsion" prevents the cartilage of one bone from physically grinding against the other.

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© 2021 by Reganemed

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